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1

The NIH BRAIN Initiative: Integrating Neuroethics and Neuroscience

Ramos, Khara M., Grady, Christine, Greely, Henry T., Chiong, Winston, Eberwine, James, Farahany, Nita A., Johnson, L.Syd M., Hyman, Bradley T., Hyman, Steven E., Rommelfanger, Karen S., Serrano, Elba

Journal:

Year:

2019

Language:

english

File:

PDF, 858 KB

english, 2019

2

Neuroethics Guiding Principles for the NIH BRAIN Initiative

Greely, Henry T., Grady, Christine, Ramos, Khara M., Chiong, Winston, Eberwine, James, Farahany, Nita A., Johnson, L. Syd M, Hyman, Bradley T., Hyman, Steven E., Rommelfanger, Karen S., Serrano, Elba

Journal:

Journal of Neuroscience

Year:

2018

Language:

english

File:

PDF, 79 KB

english, 2018

3

Implications of Recent Neuroscientific Findings in Patients with Disorders of Consciousness

L. Syd M. Johnson

Journal:

Year:

2010

Language:

english

File:

PDF, 208 KB

english, 2010

4

Return to Play Guidelines Cannot Solve the Football-Related Concussion Problem

L. Syd M. Johnson

Journal:

Journal of School Health

Year:

2012

Language:

english

File:

PDF, 585 KB

english, 2012

5

Humanized Monoclonal Antibody against West Nile Virus Envelope Protein Administered after Neuronal Infection Protects against Lethal Encephalitis in Hamsters

Morrey, John D., Siddharthan, Venkatraman, Olsen, Aaron L., Roper, Grant Y., Wang, Hong, Baldwin, Thomas J., Koenig, Scott, Johnson, Syd, Nordstrom, Jeffrey L., Diamond, Michael S.

Journal:

The Journal of Infectious Diseases

Year:

2006

Language:

english

File:

PDF, 7.31 MB

english, 2006

6

The Sources of Uncertainty in Disorders of Consciousness

Johnson, L. Syd M, Lazaridis, Christos

Journal:

AJOB Neuroscience

Year:

2018

Language:

english

File:

PDF, 530 KB

english, 2018

7

Optimal therapeutic activity of monoclonal antibodies against chikungunya virus requires Fc-FcγR interaction on monocytes

Fox, Julie M., Roy, Vicky, Gunn, Bronwyn M., Huang, Ling, Edeling, Melissa A., Mack, Matthias, Fremont, Daved H., Doranz, Benjamin J., Johnson, Syd, Alter, Galit, Diamond, Michael S.

Journal:

Science Immunology

Year:

2019

Language:

english

File:

PDF, 1.08 MB

english, 2019

8

A Belmont Report for Animals?

FERDOWSIAN, HOPE, JOHNSON, L. SYD M, JOHNSON, JANE, FENTON, ANDREW, SHRIVER, ADAM, GLUCK, JOHN

Journal:

Cambridge Quarterly of Healthcare Ethics

Year:

2019

Language:

english

File:

PDF, 552 KB

english, 2019

9

IgG antibodies produced during subcutaneous allergen immunotherapy mediate inhibition of basophil activation via a mechanism involving both FcγRIIA and FcγRIIB

Carol T. Cady, Maree S. Powell, Ronald J. Harbeck, Patricia C. Giclas, James R. Murphy, Rohit K. Katial, Richard W. Weber, P. Mark Hogarth, Syd Johnson, Ezio Bonvini, Scott Koenig, John C. Cambier

Journal:

Immunology Letters

Year:

2010

Language:

english

File:

PDF, 879 KB

english, 2010

10

Monoclonal antibodies capable of discriminating the human inhibitory Fcγ-receptor IIB (CD32B) from the activating Fcγ-receptor IIA (CD32A): biochemical, biological and functional characterization

Maria-Concetta Veri, Sergey Gorlatov, Hua Li, Steve Burke, Syd Johnson, Jeffrey Stavenhagen, Kathryn E. Stein, Ezio Bonvini, Scott Koenig

Journal:

Year:

2007

Language:

english

File:

PDF, 1006 KB

english, 2007

11

Contribution of novel choline-binding proteins to adherence, colonization and immunogenicity of Streptococcus pneumoniae

Carsten Rosenow, Patricia Ryan, Jeffrey N. Weiser, Syd Johnson, Patricia Fontan, Ake Ortqvist, H. Robert Masure

Journal:

Molecular Microbiology

Year:

1997

Language:

english

File:

PDF, 676 KB

english, 1997

12

Structural basis of West Nile virus neutralization by a therapeutic antibody

Nybakken, Grant E., Oliphant, Theodore, Johnson, Syd, Burke, Stephen, Diamond, Michael S., Fremont, Daved H.

Journal:

Year:

2005

Language:

english

File:

PDF, 531 KB

english, 2005

13

Development of a humanized monoclonal antibody with therapeutic potential against West Nile virus

Oliphant, Theodore, Engle, Michael, Nybakken, Grant E, Doane, Chris, Johnson, Syd, Huang, Ling, Gorlatov, Sergey, Mehlhop, Erin, Marri, Anantha, Chung, Kyung Min

Journal:

Nature Medicine

Year:

2005

Language:

english

File:

PDF, 773 KB

english, 2005

14

West Nile virus—induced acute flaccid paralysis is prevented by monoclonal antibody treatment when administered after infection of spinal cord neurons

John D. Morrey, Venkatraman Siddharthan, Hong Wang, Jeffery O. Hall, Ramona T. Skirpstunas, Aaron L. Olsen, Jeffrey L. Nordstrom, Scott Koenig, Syd Johnson, Michael S. Diamond

Journal:

Journal of NeuroVirology

Year:

2008

Language:

english

File:

PDF, 5.14 MB

english, 2008

15

Enhancing the potency of therapeutic monoclonal antibodies via Fc optimization

Jeffrey B. Stavenhagen, Sergey Gorlatov, Nadine Tuaillon, Christopher T. Rankin, Hua Li, Stephen Burke, Ling Huang, Syd Johnson, Scott Koenig, Ezio Bonvini

Journal:

Advances in Enzyme Regulation

Year:

2008

Language:

english

File:

PDF, 610 KB

english, 2008

16

Treatment of Paralysis Caused by West Nile Virus in Hamsters

John D. Morrey, Venkatraman Siddharthan, Hong Wang, Aaron L. Olsen, Ramona Skirpstunas, Jeffery O. Hall, Hua Li, Scott Koenig, Syd Johnson, Jeffrey L. Nordstrom, Nicole Marlenee, Richard A. Bowen, Mic

Journal:

Antiviral Research

Year:

2007

Language:

english

File:

PDF, 60 KB

english, 2007

17

Dengue virus neutralization is modulated by IgG antibody subclass and Fcγ receptor subtype

W.W. Shanaka I. Rodrigo, Olivia K.T. Block, Christopher Lane, Soila Sukupolvi-Petty, Ana P. Goncalvez, Syd Johnson, Michael S. Diamond, Ching-Juh Lai, Robert C. Rose, Xia Jin, Jacob J. Schlesinger

Journal:

Year:

2009

Language:

english

File:

PDF, 650 KB

english, 2009

18

Complement Protein C1q Inhibits Antibody-Dependent Enhancement of Flavivirus Infection in an IgG Subclass-Specific Manner

Erin Mehlhop, Camilo Ansarah-Sobrinho, Syd Johnson, Michael Engle, Daved H. Fremont, Theodore C. Pierson, Michael S. Diamond

Journal:

Cell Host & Microbe

Year:

2007

Language:

english

File:

PDF, 976 KB

english, 2007

19

Complement Protein C1q Reduces the Stoichiometric Threshold for Antibody-Mediated Neutralization of West Nile Virus

Erin Mehlhop, Steevenson Nelson, Christiane A. Jost, Sergey Gorlatov, Syd Johnson, Daved H. Fremont, Michael S. Diamond, Theodore C. Pierson

Journal:

Cell Host & Microbe

Year:

2009

Language:

english

File:

PDF, 602 KB

english, 2009

20

Development of Motavizumab, an Ultra-potent Antibody for the Prevention of Respiratory Syncytial Virus Infection in the Upper and Lower Respiratory Tract

Herren Wu, David S. Pfarr, Syd Johnson, Yambasu A. Brewah, Robert M. Woods, Nita K. Patel, Wendy I. White, James F. Young, Peter A. Kiener

Journal:

Journal of Molecular Biology

Year:

2007

Language:

english

File:

PDF, 1023 KB

english, 2007

21

Effector Cell Recruitment with Novel Fv-based Dual-affinity Re-targeting Protein Leads to Potent Tumor Cytolysis and in Vivo B-cell Depletion

Syd Johnson, Stephen Burke, Ling Huang, Sergey Gorlatov, Hua Li, Weili Wang, Wenjun Zhang, Nadine Tuaillon, Jonah Rainey, Bhaswati Barat, Yinhua Yang, Linda Jin, Valentina Ciccarone, Paul A. Moore, Sc

Journal:

Journal of Molecular Biology

Year:

2010

Language:

english

File:

PDF, 1.11 MB

english, 2010

22

New concepts in monoclonal antibody based radioimmunodiagnosis and radioimmunotherapy of carcinoma

Schlom, Jeffrey, Milenic, Diane E., Roselli, Mario, Colcher, David, Bird, Robert, Johnson, Syd, Hardman, Karl D., Guadagni, Fiorella, Greiner, John W.

Journal:

International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology

Year:

1991

Language:

english

File:

PDF, 1.14 MB

english, 1991

23

Conformational stability, folding, and ligand-binding affinity of single-chain Fv immunoglobulin fragments expressed in Escherichia coli

Pantoliano, Michael W., Bird, Robert E., Johnson, Syd, Asel, Eric D., Dodd, Steven W., Wood, Jay F., Hardman, Karl D.

Journal:

Year:

1991

Language:

english

File:

PDF, 2.28 MB

english, 1991

24

The Ethically Dubious Practice of Thwarting the Redemption of the Condemned

Johnson, L. Syd M.

Journal:

American Journal of Bioethics

Year:

2011

Language:

english

File:

PDF, 73 KB

english, 2011

25

Reviews

Hargreaves, Alec, Marshall, Ineke Haen, Modood, Tariq, Crowley, John, Sander, Åke, Jeffers, Syd, Li, Peter S., Foster, Peter, Mason, David, Johnson, Mark R D

Journal:

Journal of Ethnic and Migration Studies

Year:

1998

Language:

english

File:

PDF, 1.14 MB

english, 1998

26

A Legal Fiction with Real Consequences

Johnson, L. Syd M.

Journal:

American Journal of Bioethics

Year:

2014

Language:

english

File:

PDF, 78 KB

english, 2014

27

Stable Value Sets, Psychological Well-Being, and the Disability Paradox: Ramifications for Assessing Decision-Making Capacity

Johnson, L. Syd M.

Journal:

AJOB Neuroscience

Year:

2013

Language:

english

File:

PDF, 71 KB

english, 2013

28

Development of a Humanized Monoclonal Antibody (MEDI‐493) with Potent In Vitro and In Vivo Activity against Respiratory Syncytial Virus

Johnson, Syd, Oliver, Cynthia, Prince, Gregory A., Hemming, Val G., Pfarr, David S., Wang, Sheau‐Chiann, Dormitzer, Melissa, O'Grady, John, Koenig, Scott, Tamura, James K., Woods, Robert, Bansal, Geet

Journal:

The Journal of Infectious Diseases

Year:

1997

Language:

english

File:

PDF, 178 KB

english, 1997

29

Monoclonal Antibody Produced in Plants Efficiently Treats West Nile Virus Infection in Mice

Huafang Lai, Michael Engle, Anja Fuchs, Thomas Keller, Syd Johnson, Sergey Gorlatov, Michael S. Diamond, Qiang Chen and Charles J. Arntzen

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.52 MB

english, 2010

30

A Direct Comparison of the Activities of Two Humanized Respiratory Syncytial Virus Monoclonal Antibodies: MEDI‐493 and RSHZl9

Johnson, Syd, Griego, Sandra D., Pfarr, David S., Doyle, Michael L., Woods, Robert, Carlin, David, Prince, Gregory A., Koenig, Scott, Young, James F., Dillon, Susan B.

Journal:

The Journal of Infectious Diseases

Year:

1999

Language:

english

File:

PDF, 124 KB

english, 1999

31

Sport-Related Neurotrauma and Neuroprotection: Are Return-to-Play Protocols Justified by Paternalism?

Johnson, L. Syd M

Journal:

Year:

2015

Language:

english

File:

PDF, 288 KB

english, 2015

32

What Lies Ahead for Neuroethics Scholarship and Education in Light of the Human Brain Projects?

Rommelfanger, Karen S., Johnson, L. Syd M

Journal:

AJOB Neuroscience

Year:

2015

Language:

english

File:

PDF, 50 KB

english, 2015

33

The Impact of American Tackle Football-Related Concussion in Youth Athletes

Gilbert, Frédéric, Johnson, L. Syd M.

Journal:

AJOB Neuroscience

Year:

2011

Language:

english

File:

PDF, 131 KB

english, 2011

34

Potent Dengue Virus Neutralization by a Therapeutic Antibody with Low Monovalent Affinity Requires Bivalent Engagement

Edeling, Melissa A., Austin, S. Kyle, Shrestha, Bimmi, Dowd, Kimberly A., Mukherjee, Swati, Nelson, Christopher A., Johnson, Syd, Mabila, Manu N., Christian, Elizabeth A., Rucker, Joseph, Pierson, The

Journal:

Year:

2014

Language:

english

File:

PDF, 1.27 MB

english, 2014

35

The Development of Therapeutic Antibodies That Neutralize Homologous and Heterologous Genotypes of Dengue Virus Type 1

Shrestha, Bimmi, Brien, James D., Sukupolvi-Petty, Soila, Austin, S. Kyle, Edeling, Melissa A., Kim, Taekyung, O'Brien, Katie M., Nelson, Christopher A., Johnson, Syd, Fremont, Daved H., Diamond, Mich

Journal:

Year:

2010

Language:

english

File:

PDF, 915 KB

english, 2010

36

Lethal Antibody Enhancement of Dengue Disease in Mice Is Prevented by Fc Modification

Balsitis, Scott J., Williams, Katherine L., Lachica, Ruben, Flores, Diana, Kyle, Jennifer L., Mehlhop, Erin, Johnson, Syd, Diamond, Michael S., Beatty, P. Robert, Harris, Eva, Baric, Ralph S.

Journal:

Year:

2010

Language:

english

File:

PDF, 917 KB

english, 2010

37

Therapeutic Efficacy of Antibodies Lacking FcγR against Lethal Dengue Virus Infection Is Due to Neutralizing Potency and Blocking of Enhancing Antibodies

Williams, Katherine L., Sukupolvi-Petty, Soila, Beltramello, Martina, Johnson, Syd, Sallusto, Federica, Lanzavecchia, Antonio, Diamond, Michael S., Harris, Eva, Fernandez-Sesma, Ana

Journal:

Year:

2013

Language:

english

File:

PDF, 1.14 MB

english, 2013

38

Structural Basis of Differential Neutralization of DENV-1 Genotypes by an Antibody that Recognizes a Cryptic Epitope

Austin, S. Kyle, Dowd, Kimberly A., Shrestha, Bimmi, Nelson, Christopher A., Edeling, Melissa A., Johnson, Syd, Pierson, Theodore C., Diamond, Michael S., Fremont, Daved H., Rey, Félix A.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.04 MB

english, 2012

39

Development of a Highly Protective Combination Monoclonal Antibody Therapy against Chikungunya Virus

Pal, Pankaj, Dowd, Kimberly A., Brien, James D., Edeling, Melissa A., Gorlatov, Sergey, Johnson, Syd, Lee, Iris, Akahata, Wataru, Nabel, Gary J., Richter, Mareike K. S., Smit, Jolanda M., Fremont, Dav

Journal:

Year:

2013

Language:

english

File:

PDF, 2.02 MB

english, 2013

40

Capturing a Flavivirus Pre-Fusion Intermediate

Kaufmann, Bärbel, Chipman, Paul R., Holdaway, Heather A., Johnson, Syd, Fremont, Daved H., Kuhn, Richard J., Diamond, Michael S., Rossmann, Michael G., Baric, Ralph S.

Journal:

Year:

2009

Language:

english

File:

PDF, 673 KB

english, 2009

41

Defining New Therapeutics Using a More Immunocompetent Mouse Model of Antibody-Enhanced Dengue Virus Infection

Pinto, Amelia K., Brien, James D., Lam, Chia-Ying Kao, Johnson, Syd, Chiang, Cindy, Hiscott, John, Sarathy, Vanessa V., Barrett, Alan D., Shresta, Sujan, Diamond, Michael S.

Journal:

Year:

2015

Language:

english

File:

PDF, 4.15 MB

english, 2015

42

Molecular Characterization of Five Human Anti-Human Immunodeficiency Virus Type 1 Antibody Heavy Chains Reveals Extensive Somatic Mutation Typical of an Antigen-Driven Immune Response

Jennifer S. Andris, Syd Johnson, Susan Zolla-Pazner and J. Donald Capra

Journal:

Proceedings of the National Academy of Sciences

Year:

1991

Language:

english

File:

PDF, 1.01 MB

english, 1991

43

The Case for Reasonable Accommodation of Conscientious Objections to Declarations of Brain Death

Johnson, L. Syd M.

Journal:

Journal of Bioethical Inquiry

Year:

2016

Language:

english

File:

PDF, 346 KB

english, 2016

44

[Methods in Enzymology] Molecular Design and Modeling: Concepts and Applications Part B: Antibodies and Antigens, Nucleic Acids, Polysaccharides, and Drugs Volume 203 || [4] Construction of single-chain Fv derivatives of monoclonal antibodies and their production in Escherichia coli

Year:

1991

Language:

english

File:

PDF, 747 KB

english, 1991

45

Inference and Inductive Risk in Disorders of Consciousness

Johnson, L. Syd M.

Journal:

AJOB Neuroscience

Year:

2016

Language:

english

File:

PDF, 373 KB

english, 2016

46

Framing the Debate: Concussion and Mild Traumatic Brain Injury

Johnson, L. Syd M., Partridge, Brad, Gilbert, Frédéric

Journal:

Year:

2015

Language:

english

File:

PDF, 100 KB

english, 2015

47

Delayed treatment with W1-mAb, a chimpanzee-derived monoclonal antibody against protective antigen, reduces mortality from challenges with anthrax edema or lethal toxin in rats and with anthrax spores in mice

Altaweel, Laith, Chen, Zhaochun, Moayeri, Mahtab, Cui, Xizhong, Li, Yan, Su, Junwu, Fitz, Yvonne, Johnson, Syd, Leppla, Stephen H., Purcell, Robert, Eichacker, Peter Q.

Journal:

Critical Care Medicine

Year:

2011

Language:

english

File:

PDF, 1.13 MB

english, 2011

48

Development of a Humanized Monoclonal Antibody (MEDI-493) with Potent in vitro and in vivo Activity against Respiratory Syncytial Virus

Syd Johnson, Cynthia Oliver, Gregory A. Prince, Val G. Hemming, David S. Pfarr, Sheau-Chiann Wang, Melissa Dormitzer, John O'Grady, Scott Koenig, James K. Tamura, Robert Woods, Geetha Bansal, Debra Co

Journal:

The Journal of Infectious Diseases

Year:

1997

Language:

english

File:

PDF, 1.80 MB

english, 1997

49

A Direct Comparison of the Activities of Two Humanized Respiratory Syncytial Virus Monoclonal Antibodies: MEDI-493 and RSHZ19

Syd Johnson, Sandra D. Griego, David S. Pfarr, Michael L. Doyle, Robert Woods, David Carlin, Gregory A. Prince, Scott Koenig, James F. Young and Susan B. Dillon

Journal:

The Journal of Infectious Diseases

Year:

1999

Language:

english

File:

PDF, 1.06 MB

english, 1999

50

Death by neurological criteria: expert definitions and lay misgivings

Johnson, L. Syd M

Journal:

Year:

2016

Language:

english

File:

PDF, 81 KB

english, 2016